Cytomegalovirus (CMV) is one of the most common infectious agents, infecting the general population at an early age without\ncausing morbidity most of the time. However, on particular occasions, it may represent a serious risk, as active infection is\nassociated with rejection and disease after solid organ transplantation or fetal transmission during pregnancy. Several methods\nfor CMV diagnosis are available on the market, but because infection is so common, careful selection is needed to discriminate\nprimary infection from reactivation.This review focuses on methods based on CMV-specific T cell reactivity to help monitor the\nconsequences of CMV infection/reactivation in specific categories of patients. This review makes an attempt at discussing the pros\nand cons of the methods available.
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